Facebook founder Mark Zuckerberg announced the departure of company product manager Chris Cox and director of WhatsApp Chris Daniels.
Mr. Cox joined in 2005, a year after Facebook was founded, while Daniels took over his role just a year ago.
No reason was explicitly given for their departure.
The changes come shortly after Mr. Zuckerberg outlined his plan to turn Facebook into a "privacy-focused platform."
This week the social media giant and its WhatsApp and Instagram platforms have also experienced the worst interruption in the company's history. Facebook has blamed a "server configuration change" blackout.
- Facebook renews privacy controls
- WhatsApp, Instagram and Messenger merge
Mr Cox, a confidant of Mr. Zuckerberg, started as a software engineer at the company and helped create different functionalities key, including News Feed.
He has also held several senior roles, directing human resources and helping to launch the Facebook Workplace trading platform.
In a separate Facebook post, Mr Cox addressed the recent proposal to move Facebook further to encrypted private communications. [1
He did not give a reason to leave, but Mr. Zuckerberg insisted that "he was discussing … his desire to do something else" for several years.
Mr. Daniels, meanwhile, started as head of Whatsapp after five years of running Internet.org, an initiative to increase Internet connectivity worldwide.
He will be replaced by Will Cathcart, who currently directs the Facebook mobile app. Fidji Simo, who ran the app while Cathcart was absent on paternity leave, will assume his role.
No replacement has been announced for Mr Cox.
Facebook has lost several top managers over the past two years, including its legal advisor, security chief and co-founders of WhatsApp, Instagram and Oculus, a virtual reality company acquired in 2014.
Facebook is been harshly criticized in the past for the lack of user privacy and the dissemination of offensive content and misinformation.
Despite the scandal, Facebook says its user numbers have continued to grow. He says that the number of people who have accessed his site at least once a month has risen by 9% last year to 2.32 billion people.
User numbers in the United States – its second largest market – have fallen by 15 million since 2017, however, according to market research firm Edison Research.