A futuristic metalless or soft "robot" pill has just passed its first human trial in February, according to IEEE Spectrum .
The pill is designed to pierce the inside of the intestinal wall with a needle full of drugs thanks to an inflatable balloon. The first human test has successfully tested the part of the inflatable balloon in the project – the drug-filled needles will still be tested in a second trial on man.
RaniPill, developed and patented by Rani Therapeutics, has already carried out 100 animal studies and recently completed a human study – which means that one day it could revolutionize the way people inject drugs.
Once ingested and directed towards the intestine, the RaniPill shell dissolves. This releases two gases that mix to create carbon dioxide, which inflates a balloon that pushes a dissolvable needle into the intestinal wall. No springs or metal are used in the project.
And no, you will not even notice that it is there or that it inflates a balloon inside your bowel. Rani Therapeutics claims that her pill will not cause any pain, unlike injections through the skin, and could reduce the cost of "most drugs" injections.
Human trials consisted of 20 subjects, half of whom ate before taking the pill and a half fast.
The food had almost no impact, except to slow down the time needed to pass the remnants of the pill. Multiple radiographs confirmed the position of the pill as it made its way through the bodies of the subjects.
The inventor Mir Imran swallowed the pill "quite a few times" ̵