Adults can sometimes suffer from dangerous symptoms that resemble a coronavirus-related syndrome in children, researchers from the U.S. Centers for Disease Control and Prevention who call it Adult Multisystem Inflammatory Syndrome, or MIS-A, said Friday. and they say it is similar to Multisystem Inflammatory Syndrome in Children or MIS-C. Like MIS-C, MIS-A is obviously not linked to the coronavirus and sufferers may not exhibit other symptoms that would indicate a COVID-19 infection, but MIS-A has killed at least three patients and, similarly to COVID-19, it disproportionately affects racial and ethnic minorities, the CDC team said. A black man living in Florida suffered from ringing in his ears, vomiting and chest pain. He tested negative for COVID-1
Adults can sometimes suffer from dangerous symptoms that resemble a coronavirus-related syndrome in children, researchers from the U.S. Centers for Disease Control and Prevention said Friday.
They call it multisystem inflammatory syndrome in adults, or MIS-A, and they say it’s similar to multisystem inflammatory syndrome in children or MIS-C. Like MIS-C, MIS-A is obviously not linked to the coronavirus, and sufferers may not show other symptoms that would indicate a COVID-19 infection.
But MIS-A has killed at least three patients and, similar to COVID-19, disproportionately affects racial and ethnic minorities, the CDC team said.
A black man living in Florida suffered from ringing in his ears, vomiting and chest pain. He tested negative for COVID-19 when he was hospitalized, but died despite treatment. He was 46.
A 22-year-old black woman in New York City was in good health until she developed a fever and chills, but she spent 19 days in the hospital before she was well enough to go home, the CDC team said.
MIS-C has affected several hundred children around the world and, if treated promptly, children recover. It causes general inflammation but patients don’t usually show classic coronavirus symptoms. Blood tests indicate that MIS-C can develop weeks after a child has recovered from a coronavirus infection, usually a case that caused mild or no symptoms.
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The CDC team described cases of 27 adults between the ages of 21 and 50 who had similar syndromes. Most had extreme inflammation throughout their body and organ malfunction, such as the heart, liver, and kidneys, but not the lungs. “Although hyperinflammation and extrapulmonary organ dysfunction have been described in hospitalized adults with severe COVID-19, these conditions are generally accompanied by respiratory failure,” they wrote in the CDC’s weekly report on death and illness, the MMWR.
“In contrast, the patients described here had minimal respiratory symptoms, hypoxemia (low oxygen content in the blood) or radiographic abnormalities in accordance with the working case definition, which was intended to distinguish MIS-A from severe Covid-19; only eight out of 16 patients had documented respiratory symptoms prior to the initiation of MIS-A. “
One third of the 27 patients tested negative for active coronavirus infection but tested positive for antibodies, which indicated they had been infected in the past. “All but one of the MIS-A patients described in this report belonged to ethnic or racial minority groups,” the researchers wrote.
“Physicians and health departments should consider MIS-A in adults with compatible signs and symptoms,” the team advised. “These patients may not have positive SARS-CoV-2 PCR or antigen test results, and antibody tests may be needed to confirm a previous SARS-CoV-2 infection.”
Symptoms include a fever that lasts 24 hours or more; chest patient and irregular heartbeats; evidence of cardiac dysfunction; gastrointestinal symptoms and skin rashes. X-rays can show lung inflammation even if patients have no symptoms.
The CDC said 10 of the 27 patients required intensive care; three were intubated and three died. In two young adults, the first symptoms were major strokes.